Traditional debates on analogical thinking, which is at the root of all knowledge about the past, were founded on the scientific-methodological postulate of the striving for increased control of conditions that affect the research situation, that is, the pre-methodological consensus on the need for objectifying, depersonalizing and regulating resea
Solving Equations Systems Using the Penguins Search Optimization
The Penguin Search Optimization (PeSOA) is an optimization method based on collaborative hunting strategy of penguins.In this work, a solving linear halter equation systems method based on PeSOA is proposed.A dual population for PeSOA part was also tested.Experimental results obtained with our proposed method compared with those obtained with class
Proteasome associated function of UCH37 is evolutionarily conserved in Plasmodium parasites
Abstract Ubiquitin C-terminal hydrolase 37 (UCH37 also known as UCHL5) is a conserved deubiquitinating enzyme (DUB) with dual roles in proteasomal degradation and chromatin remodeling in humans.Its Plasmodium falciparum ortholog, PfUCH37, is unusual in that it possesses Diffuser both DUB and deneddylating activities.While PfUCH37 is enriched in pro
The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model
Abstract Background Colorectal cancer (CRC) is the second leading cause of cancer-related death in men and women.Systemic disease with metastatic spread to distant sites such as the liver reduces the survival rate considerably.The aim of this study Zanussi ZOF35601XK Built Under Double Oven in Stainless Steel was to investigate the changes in gene
Role of the ESCRT Complexes in Telomere Biology
ABSTRACT Eukaryotic chromosomal ends are protected Diffuser by telomeres from fusion, degradation, and unwanted double-strand break repair events.Therefore, telomeres preserve genome stability and integrity.Telomere length can be maintained by telomerase, which is expressed in most human primary tumors but is not expressed in the majority of somati